AIDS Expert - Recent AIDS/HIV-related Search Questions

AIDS Expert - Recent AIDS/HIV-related Search Questions
AIDS/HIV - Expert

Monday, August 27, 2012

AIDS - What is Optimized Background Therapy (OBT)

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AIDS - What is Optimized Background Therapy (OBT)

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  1. aids optimized background therapy

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  • Safety and Efficacy of Maraviroc (MVC), a Novel CCR5 Antagonist, when Used in Combination with Optimized Background Therapy (OBT) for the Treatment of Antiretroviral-Experienced Subjects Infected with Dual/Mixed-Tropic HIV-1: 24-Week Results of a Phase 2b Exploratory Trial

  • , optimized background therapy [OBT])

  • with an optimized background therapy that must include a protease inhibitor

  • ob

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    • Objective To describe HIV-1 DNA levels from baseline (W0) to week 52 (W52) among patients receiving either interleukin-2 (IL-2) optimized background therapy (OBT) or OBT as salvage treatment

  • Enfuvirtide (ENF), the first HIV--fusion inhibitor, has shown potent and sustained antiviral activity when administered in combination with optimized background (OB) therapy to treatment-experienced, HIV-1- infected individuals and has a favourable safety profile

  • The additional 48-week optional treatment extension of the T-20 versus Optimized Regimen Only (TORO) studies evaluated long-term safety and efficacy of enfuvirtide (ENF) through week 96 in patients receiving ENF plus optimized background (OB) and patients switching to ENF plus OB from OB alone


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