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AIDS - What is Drug Concentration
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- aids drug concentration
It`s also encouraging to know that there is a clear interest in both formulations, because although we saw much higher drug concentrations in vaginal tissue with the gel, how the differences between the gel and the tablet will translate in terms of protective effect, we can`t say just yet
Using a unit of measure called a femtomole (fmol), researchers calculated 2,352 fmol of activated drug per milligram (mg) of vaginal tissue after vaginal gel use, whereas, with the tablet, the concentration achieved in tissue was less than 17 fmol/mg a more than a 100-fold difference
The concentration of activated drug in blood cells with the oral tablet was 52 fmol/million cells and less than 5 fmol/million cells with the vaginal gel more than a 20-times difference
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