AIDS - What is Pathogenesis

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AIDS - What is Pathogenesis

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1. aids pathogenesis

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• Strong indirect support for the crucial role of immune activation in AIDS pathogenesis is provided by studies of SIV infections of natural hosts, in which high levels of virus replication are not sufficient to induce progression to AIDS in the absence of increased levels of immune activation


• Review Models for AIDS pathogenesis: simian immunodeficiency virus, simian-human immunodeficiency virus and feline immunodeficiency virus infections


• While there is a broad consensus among investigators that immune activation plays an important role in AIDS pathogenesis, much debate remains as to what causes the HIV-associated immune activation

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