AIDS - What is Therapeutic Index (TI)

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AIDS - What is Therapeutic Index (TI)

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1. aids therapeutic index

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• The Academy of Managed Care Pharmacy (AMCP) opposes legislation that restricts the appropriate generic substitution of narrow therapeutic index (NTI) drugsAMCP supports allowing pharmacists, in consultation with prescribers, to exercise professional judgment, based on scientific information, when determining whether a generic drug is an appropriate substitute for its brand


• The American Society of Health-System Pharmacists (ASHP) supports the current processes used by the Food and Drug Administration (FDA) to determine bio equivalence of generic drug products, including those with a narrow therapeutic index, and to recognize the authority of the FDA to decide if additional studies are necessary to determine equivalence


• Therapeutic Index (TI) A ratio that compares the blood concentration at which a drug becomes toxic and the concentration at which the drug is effective

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